Zolpidem is used to treat insomnia (trouble sleeping). It belongs to the group of medicines called central nervous system (CNS) depressants. These medicines will slow down the nervous system. Zolpidem will help you get to sleep faster and sleep through the night. In most cases, sleep medicines should only be used for.
This includes prescription or nonprescription (over-the-counter ) medicines and herbal or vitamin supplements. Do not take other medicines unless they have been discussed with your doctor.
Keep out of the reach of children.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of zolpidem in the elderly. However, confusion, dizziness, and falling are more likely to occur in the elderly, who are more sensitive than younger adults to the effects of zolpidem.
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Zolpidem is a prescription short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to benzodiazepine receptors which are located on the gamma-aminobutyric acid receptors. Zolpidem is used for the short-term treatment of insomnia. It works.
In contrast to the benzodiazepines, which non-selectively bind to and activate all three alpha receptor subtypes, zolpidem in vitro binds the (alpha1) receptor preferentially. The (alpha1) receptor is found primarily on the Lamina IV of the sensorimotor cortical regions, substantia nigra (pars reticulata), cerebellum molecular layer, olfactory bulb, ventral thalamic complex, pons, inferior colliculus, and globus pallidus. Zolpidem is a sedative or hypnotic agent with a chemical structure unrelated to benzodiazepines, barbiturates, or other drugs with known hypnotic properties.
Zolpidem (brand name: Ambien) can be addictive when misused and can cause some very dangerous effects. Learn more.
When taken over long periods of time, zolpidem’s effects can take their toll on the brain. Beyond the short-term side effects, zolpidem has been known to cause psychological issues in long-term users, including 1:.
Short-term effects of zolpidem use include 1,2:
Nausea. Abdominal pain. Appetite changes. Hallucinations. Dry mouth or throat. Some common short-term side effects include, but are not limited to 1,2,6: Headache. Unusual dreams or nightmares. Uncontrollable body movements. Joint pain. Gastrointestinal problems, such as constipation or diarrhea.
The IUPHAR/BPS Guide to Pharmacology. zolpidem ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs.
Ligand id: 4348 Name: zolpidem.
Molecular properties generated using the CDK Contact us.
View more information in the IUPHAR Pharmacology Education Project: zolpidem.
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